BTB-1, CAS [[86030-08-2]]

Produktübersicht

• Artikelname: BTB-1, CAS [[86030-08-2]]
• Artikelnummer: FBM-10-1543
• Hersteller Artikelnummer: 10-1543
• Alternativnummer: FBM-10-1543-10MG, FBM-10-1543-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 4-Chloro-2-nitro-1-(phenylsulfonyl)-benzene. Alternate Names: NSC 156750

Produktbeschreibung

Mitotic kinesin Kif18A inhibitor

Produkteigenschaften

• Molekulargewicht: 297.71
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: White or off-white solid
• CAS Nummer: [86030-08-2]
• Formel: C12H8ClNO4S

Anwendungsbeschreibung

• Anwendungsbeschreibung: A selective, ATP-competitive and reversible inhibitor of mitotic kinesin Kif18A, IC50=1.7 M.1,2 Binds to an allosteric site near Kif18A loop 5 preventing a range of conformational changes thereby blocking motor function.3 Inhibits the differentiation of mouse bone marrow cells to dendritic cells.4 Suppresses the replication of influenza A virus, inhibiting activation of AKT, p38 MAPK, SAPK and RanBP3 leading to the prevention of nuclear export of viral ribonucleoprotein complexes. Greatly improves the viability of IAV-infected mice.5