UCF-101, CAS [[313649-08-0]]

Produktübersicht

• Artikelname: UCF-101, CAS [[313649-08-0]]
• Artikelnummer: FBM-10-1544
• Hersteller Artikelnummer: 10-1544
• Alternativnummer: FBM-10-1544-5MG, FBM-10-1544-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: Dihydro-5[[5-(2-nitrophenyl)-2-furanyl]methylene]-1,3-diphenyl-2-thioxo-4,6(1H,5H)-pyrimidinedione

Produktbeschreibung

Omi/HtrA2 protease inhibitor

Produkteigenschaften

• Molekulargewicht: 495.51
• Reinheit: 98% by TLC
• Formulierung: Orange solid
• CAS Nummer: [313649-08-0]
• Formel: C27H17N3O5S

Anwendungsbeschreibung

• Anwendungsbeschreibung: UCF-101 is a potent, specific, competitive, and reversible inhibitor of the pro-apoptotic, mitochondrial serine protease Omi/HtrA2 (IC50 = 9.5 µM for His-Omi134-458). Shows very little activity against various other serine proteases tested (IC50 200 µM).1 Mitigates streptozotocin-induced cardiomyocyte dysfunction.2 Protects against cerebral oxidative injury and cognitive impairment in a rat model.3 Cell permeable.