ML241, CAS [[1346528-06-0]]

Produktübersicht

• Artikelname: ML241, CAS [[1346528-06-0]]
• Artikelnummer: FBM-10-1555
• Hersteller Artikelnummer: 10-1555
• Alternativnummer: FBM-10-1555-5MG, FBM-10-1555-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N-Benzyl-2-(2,3-dihydro-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydroquinazolin-4-amine. Alternate Names: CID49830260

Produktbeschreibung

p97 AAA ATPase inhibitor

Produkteigenschaften

• Molekulargewicht: 372.46
• Reinheit: 98% by HPLC NMR (conforms)
• Formulierung: Pale yellow solid
• CAS Nummer: [1346528-06-0]
• Formel: C23H24N4O

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent and selective p97 AAA ATPase inhibitor, IC50=100 nM. Inhibits degradation of a p97-dependent but not p97-independent proteasome substrate in a dual-reporter cell line1. It impairs the endoplasmic reticulum-associated degradation (ERAD) pathway.1 ML241 and related inhibitors (DBeQ for example) have differential responses to p97 mutants as well as the presence of cofactors suggesting the possibility of context-dependent p97 inhibitors.2,3