Seriniquinone, CAS [[22200-69-7]]

Produktübersicht

• Artikelname: Seriniquinone, CAS [[22200-69-7]]
• Artikelnummer: FBM-10-1608
• Hersteller Artikelnummer: 10-1608
• Alternativnummer: FBM-10-1608-1MG, FBM-10-1608-5MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: Dinaphthol[2,3-b:2,3-d]thiophene-5,7,12,13-tetraone

Produktbeschreibung

Autophagy inducer

Produkteigenschaften

• Molekulargewicht: 344.34
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: Orange solid
• CAS Nummer: [22200-69-7]
• Formel: C20H8O4S

Anwendungsbeschreibung

• Anwendungsbeschreibung: A new natural product isolated from a marine bacterium of the genus Serinicoccus. Displays selective toxicity against a distinct set of cell lines (within the NCI 60 panel) predominantly melanoma. Upon cellular treatment, seriniquinone was found to localize in the endoplasmic reticulum. Within 3 hours cells underwent autophagy followed by death via a caspase-9 apoptotic pathway. The target of seriniquinone was identified as the small protein, dermcidin as determined using an immunoaffinity approach.1