Dienamide A2, CAS [[24738-51-0]]

Produktübersicht

• Artikelname: Dienamide A2, CAS [[24738-51-0]]
• Artikelnummer: FBM-10-1621
• Hersteller Artikelnummer: 10-1621
• Alternativnummer: FBM-10-1621-5MG,FBM-10-1621-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Novel cannabinoid CB2 agonist, antiinflammatory

Produkteigenschaften

• Molekulargewicht: 251.41
• Reinheit: 98% by TLC NMR conforms
• Formulierung: White solid
• CAS Nummer: [24738-51-0]
• Formel: C16H29NO

Anwendungsbeschreibung

• Anwendungsbeschreibung: Analog of the natural amides occurring in Echinacea which represent a new class of cannabinomimetic compounds. This class of compounds modulates TNFalpha mRNA expression in human monocytes/macrophages via the CB2 receptor.1 Dienamide A2 binds to cannabinoid receptors with greater affinity than endogenous cannabinoids (Ki= ~60 and >1500 nM for CB2 and CB1 respectively)2. It elevates intracellular Ca2+ levels in CB2-positive but not in CB2-negative cells and this effect was blocked by SR144528.2 It significantly inhibits LPS-induced TNFalpha and IL-1beta expression in a CB2-independent manner.2