Ezetimibe, CAS [[163222-33-1]]

Produktübersicht

• Artikelname: Ezetimibe, CAS [[163222-33-1]]
• Artikelnummer: FBM-10-2027
• Hersteller Artikelnummer: 10-2027
• Alternativnummer: FBM-10-2027-20MG, FBM-10-2027-100MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidine-2-one. Alternate Names: SCH 58235, Ezetrol

Produktbeschreibung

Cholesterol absorption inhibitor

Produkteigenschaften

• Molekulargewicht: 409.43
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: White or off-white solid
• CAS Nummer: [163222-33-1]
• Formel: C24H21F2NO3

Anwendungsbeschreibung

• Anwendungsbeschreibung: Inhibits cholesterol absorption in the intestine by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter.1 Undergoes rapid glucuronidation in the intestine where its glucuronide binds NPC1L1.2 Inhibits dengue virus infection in Huh-7 cells by blocking cholesterol transport.3 Ameliorates steatohepatitis by activation of autophagy and inhibition of NLRP3 inflammasome.4