Ezetimibe, CAS [[163222-33-1]]

Product Overview

• Article Name: Ezetimibe, CAS [[163222-33-1]]
• Biozol Catalog Number: FBM-10-2027
• Supplier Catalog Number: 10-2027
• Alternative Catalog Number: FBM-10-2027-20MG, FBM-10-2027-100MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidine-2-one. Alternate Names: SCH 58235, Ezetrol

Product Description

Cholesterol absorption inhibitor

Product Properties

• Molecular Weight: 409.43
• Purity: 98% by TLC NMR (Conforms)
• Form: White or off-white solid
• CAS Number: [163222-33-1]
• Formula: C24H21F2NO3

Application Notes

• Application Notes: Inhibits cholesterol absorption in the intestine by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter.1 Undergoes rapid glucuronidation in the intestine where its glucuronide binds NPC1L1.2 Inhibits dengue virus infection in Huh-7 cells by blocking cholesterol transport.3 Ameliorates steatohepatitis by activation of autophagy and inhibition of NLRP3 inflammasome.4