Apicidin, CAS [[183506-66-3]]

Produktübersicht

• Artikelname: Apicidin, CAS [[183506-66-3]]
• Artikelnummer: FBM-10-2057
• Hersteller Artikelnummer: 10-2057
• Alternativnummer: FBM-10-2057-1MG, FBM-10-2057-5MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: Cyclo[(2S)-2-amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinexcarbonyl]

Produktbeschreibung

HDAC inhibitor

Produkteigenschaften

• Molekulargewicht: 623.78
• Reinheit: >98%
• Formulierung: White solid
• CAS Nummer: [183506-66-3]
• Formel: C34H49N5O6

Anwendungsbeschreibung

• Anwendungsbeschreibung: Apicidin is a fungal toxin that is a potent, cell permeable inhibitor of histone deacetylases (HDACs).1 It also displays antitumor properties by inducing changes in p21WAF1/Cip1 and gelsolin gene expression causing cell cycle arrest in the G1 phase.2 Apicidin dramatically decreases HIF-1alpha protein levels and transcriptional activity in human and mouse tumor cell lines.3