Gliotoxin, CAS [[67-99-2]]

Produktübersicht

• Artikelname: Gliotoxin, CAS [[67-99-2]]
• Artikelnummer: FBM-10-2076
• Hersteller Artikelnummer: 10-2076
• Alternativnummer: FBM-10-2076-1MG, FBM-10-2076-5MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (3R,5aS,6S,10aR)-2,3,5a,6-Tetrahydro-6-hydroxy-3-(hydroxymethyl)-2-methyl-10H-3,10a-epidithiopyrazino [1,2-a]indole-1,4-dione. Alternate Names: Aspergillin

Produktbeschreibung

Immunomodulator

Produkteigenschaften

• Molekulargewicht: 326.39
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: White lyophilized solid
• CAS Nummer: [67-99-2]
• Formel: C13H14N2O4S2

Anwendungsbeschreibung

• Anwendungsbeschreibung: A fungal metabolite with immunosuppressive properties, blocks phagocytosis, cytokine production and proliferation of T and B cells.1 Inhibits chymotrypsin-like activity of 20S proteasome preventing IkappaBalpha degradation and preventing NF-kappaB degradation2. Displays antiinflammatory activity3 and blocks leukotriene B4 production via inhibition of LTA4 hydrolase4. It inhibits nuclear NOTCH2 and recovers a tumor-suppressor NOTCH3 activity in chronic lymphocytic leukemia cells.5