Gliotoxin, CAS [[67-99-2]]

Product Overview

• Article Name: Gliotoxin, CAS [[67-99-2]]
• Biozol Catalog Number: FBM-10-2076
• Supplier Catalog Number: 10-2076
• Alternative Catalog Number: FBM-10-2076-1MG,FBM-10-2076-5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Aspergillin

Product Description

Immunomodulator

Product Properties

• Molecular Weight: 326.39
• Purity: 98% by HPLC NMR (Conforms)
• Form: White lyophilized solid
• CAS Number: [67-99-2]
• Formula: C13H14N2O4S2

Application Notes

• Application Notes: A fungal metabolite with immunosuppressive properties, blocks phagocytosis, cytokine production and proliferation of T and B cells.1 Inhibits chymotrypsin-like activity of 20S proteasome preventing IkappaBalpha degradation and preventing NF-kappaB degradation2. Displays antiinflammatory activity3 and blocks leukotriene B4 production via inhibition of LTA4 hydrolase4. It inhibits nuclear NOTCH2 and recovers a tumor-suppressor NOTCH3 activity in chronic lymphocytic leukemia cells.5