Myriocin (ISP-1), CAS [[35891-70-4]]

Produktübersicht

• Artikelname: Myriocin (ISP-1), CAS [[35891-70-4]]
• Artikelnummer: FBM-10-2088
• Hersteller Artikelnummer: 10-2088
• Alternativnummer: FBM-10-2088-5MG, FBM-10-2088-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid. Alternate Names: ISP-1

Produktbeschreibung

Blocks sphingolipid biosynthesis

Produkteigenschaften

• Molekulargewicht: 401.54
• Reinheit: >98%
• Formulierung: Off-white solid
• CAS Nummer: [35891-70-4]
• Formel: C21H39NO6

Anwendungsbeschreibung

• Anwendungsbeschreibung: Myriocin is a fungal metabolite with potent immunosuppressant activity.1 It inhibits serine palmitoyltransferase (Ki = 0.28 nM) blocking the synthesis of ceramide.2 It was found to suppress melanoma cell proliferation by cell cycle arrest at the G 2/M phase through decreased sphingolipid levels and increased p53 and p21 (waf1/cip1) expression.3