Bexarotene, CAS [[153559-49-0]]

Produktübersicht

• Artikelname: Bexarotene, CAS [[153559-49-0]]
• Artikelnummer: FBM-10-2121
• Hersteller Artikelnummer: 10-2121
• Alternativnummer: FBM-10-2121-10MG, FBM-10-2121-100MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid. Alternate Names: LGD-1069, SR-11247

Produktbeschreibung

Retinoid RXR agonist

Produkteigenschaften

• Molekulargewicht: 348.49
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [153559-49-0]
• Formel: C24H28O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: A highly potent and selective retinoid X receptor (RXR) agonist (EC50=28, 25, 20 nM for RXRalpha, beta, gamma respectively)1. Clinically useful antineoplastic agent for cutaneous T-cell lymphoma2 Causes complete regression of mammary carcinoma3. Bexarotene significantly increases clearance of soluble beta-amyloid in a mouse Alzheimer's model and increases cognitive ability4. Reverses apoE4-driven brain pathology and behavioral deficits in vivo5.