Bexarotene, CAS [[153559-49-0]]

Product Overview

• Article Name: Bexarotene, CAS [[153559-49-0]]
• Biozol Catalog Number: FBM-10-2121
• Supplier Catalog Number: 10-2121
• Alternative Catalog Number: FBM-10-2121-10MG, FBM-10-2121-100MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid. Alternate Names: LGD-1069, SR-11247

Product Description

Retinoid RXR agonist

Product Properties

• Molecular Weight: 348.49
• Purity: 98% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [153559-49-0]
• Formula: C24H28O2

Application Notes

• Application Notes: A highly potent and selective retinoid X receptor (RXR) agonist (EC50=28, 25, 20 nM for RXRalpha, beta, gamma respectively)1. Clinically useful antineoplastic agent for cutaneous T-cell lymphoma2 Causes complete regression of mammary carcinoma3. Bexarotene significantly increases clearance of soluble beta-amyloid in a mouse Alzheimer's model and increases cognitive ability4. Reverses apoE4-driven brain pathology and behavioral deficits in vivo5.