Chemical Name: 1-[5-tert-Butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalene-1-yl]urea. Alternate Names: BIRB-796
p38 MAPK inhibitor
Molekulargewicht:
527.66
Reinheit:
98% by TLC, NMR (Conforms)
Formulierung:
White or off-white solid
CAS Nummer:
[285983-48-4]
Formel:
C31H37N5O3
Anwendungsbeschreibung:
Potently and selectively inhibits p38 MAPK by simultaneously binding to the ATP-binding domain and an allosteric site.1 (IC50=18 nM). Displays anti-inflammatory activity2 but differential effects on inflammatory genes3. Cell permeable.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten