Doramapimod, CAS [[285983-48-4]]

Product Overview

• Article Name: Doramapimod, CAS [[285983-48-4]]
• Biozol Catalog Number: FBM-10-2128
• Supplier Catalog Number: 10-2128
• Alternative Catalog Number: FBM-10-2128-5MG, FBM-10-2128-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 1-[5-tert-Butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalene-1-yl]urea. Alternate Names: BIRB-796

Product Description

p38 MAPK inhibitor

Product Properties

• Molecular Weight: 527.66
• Purity: 98% by TLC, NMR (Conforms)
• Form: White or off-white solid
• CAS Number: [285983-48-4]
• Formula: C31H37N5O3

Application Notes

• Application Notes: Potently and selectively inhibits p38 MAPK by simultaneously binding to the ATP-binding domain and an allosteric site.1 (IC50=18 nM). Displays anti-inflammatory activity2 but differential effects on inflammatory genes3. Cell permeable.