Enzastaurin, CAS [[170364-57-5]]

Produktübersicht

• Artikelname: Enzastaurin, CAS [[170364-57-5]]
• Artikelnummer: FBM-10-2132
• Hersteller Artikelnummer: 10-2132
• Alternativnummer: FBM-10-2132-5MG, FBM-10-2132-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3-(1-Methyl-1H-indol-3-yl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione. Alternate Names: LY-317615

Produktbeschreibung

PKC inhibitor

Produkteigenschaften

• Molekulargewicht: 515.61
• Reinheit: 99% by HPLC, NMR (Conforms)
• Formulierung: Orange solid
• CAS Nummer: [170364-57-5]
• Formel: C32H29N5O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent and selective PKCbeta inhibitor. IC50 = 6, 39, 83 and 110 nM, for PKCbeta, PKCalpha, PKCgamma and PKCepsilon respectively.1 Induces apoptosis in multiple myeloma cell lines via inhibition of the AKT signaling pathway.2 Induces mitotic missegregation and preferential cytotoxicity in colorectal cancer cells with chromosomal instability.3 Attenuates ampheta-mine-stimulated dopamine efflux.4 Inhibits blood-brain barrier leakiness in a mouse model.5