Enzastaurin, CAS [[170364-57-5]]

Product Overview

• Article Name: Enzastaurin, CAS [[170364-57-5]]
• Biozol Catalog Number: FBM-10-2132
• Supplier Catalog Number: 10-2132
• Alternative Catalog Number: FBM-10-2132-5MG,FBM-10-2132-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: LY-317615

Product Description

PKC inhibitor

Product Properties

• Molecular Weight: 515.61
• Purity: 99% by HPLC, NMR (Conforms)
• Form: Orange solid
• CAS Number: [170364-57-5]
• Formula: C32H29N5O2

Application Notes

• Application Notes: Potent and selective PKCbeta inhibitor. IC50 = 6, 39, 83 and 110 nM, for PKCbeta, PKCalpha, PKCgamma and PKCepsilon respectively.1 Induces apoptosis in multiple myeloma cell lines via inhibition of the AKT signaling pathway.2 Induces mitotic missegregation and preferential cytotoxicity in colorectal cancer cells with chromosomal instability.3 Attenuates ampheta-mine-stimulated dopamine efflux.4 Inhibits blood-brain barrier leakiness in a mouse model.5