H89 2HCl, CAS [[127243-85-0]]

Produktübersicht

• Artikelname: H89 2HCl, CAS [[127243-85-0]]
• Artikelnummer: FBM-10-2144
• Hersteller Artikelnummer: 10-2144
• Alternativnummer: FBM-10-2144-5MG, FBM-10-2144-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N-[2-[[3-(4-Bromophenyl)-2-propen-1-yl]amino]ethyl]-5-isoquinolinesulfonamide dihydrochloride

Produktbeschreibung

PKA inhibitor

Produkteigenschaften

• Molekulargewicht: 519.28
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [127243-85-0]
• Formel: C20H20BrN3O2S2HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: H-89 is a commonly used inhibitor of protein kinase A (PKA IC50 = 140 nM). Inhibits a variety of other kinases including S6K1 (IC50 = 80 nM), MSK1 (120 nM), ROCK II (270 nM), PKBalpha (2.6 µM), PKD, PRK2, RSK1 and 2, SGK, AMPK, CHK1 and MAPKAP-K1b (2.8 µM).1,2