PD 325901, CAS [[391210-10-9]]

Artikelnummer: FBM-10-2161
Artikelname: PD 325901, CAS [[391210-10-9]]
Artikelnummer: FBM-10-2161
Hersteller Artikelnummer: 10-2161
Alternativnummer: FBM-10-2161-5MG, FBM-10-2161-25MG, FBM-10-2161-10MM/1MLDMSO
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Alternative Synonym: Chemical Name: N-[(2R(-))-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
MEK inhibitor
Molekulargewicht: 482.20
Reinheit: 98%, NMR Conforms
Formulierung: White solid
CAS Nummer: [391210-10-9]
Formel: C16H14F3IN2O4
Anwendungsbeschreibung: A selective non-ATP competitive MEK inhibitor (IC50 = 0.33 nM).1 Inhibits growth and/or proliferation of a variety of cancer cells.2 Enhances self-renewal of embryonic stem cells.3 In combination with vitamin C, synergistically induces hypomethylation of mouse embryonic stem cells.4 In combination with CHIR-99021 and A83-01 induces generation of ground state iPS cells from human and rat somatic cells.5