PD 325901, CAS [[391210-10-9]]

Product Overview

• Article Name: PD 325901, CAS [[391210-10-9]]
• Biozol Catalog Number: FBM-10-2161
• Supplier Catalog Number: 10-2161
• Alternative Catalog Number: FBM-10-2161-5MG, FBM-10-2161-25MG, FBM-10-2161-10MM/1MLDMSO
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-[(2R(-))-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide

Product Description

MEK inhibitor

Product Properties

• Molecular Weight: 482.20
• Purity: 98%, NMR Conforms
• Form: White solid
• CAS Number: [391210-10-9]
• Formula: C16H14F3IN2O4

Application Notes

• Application Notes: A selective non-ATP competitive MEK inhibitor (IC50 = 0.33 nM).1 Inhibits growth and/or proliferation of a variety of cancer cells.2 Enhances self-renewal of embryonic stem cells.3 In combination with vitamin C, synergistically induces hypomethylation of mouse embryonic stem cells.4 In combination with CHIR-99021 and A83-01 induces generation of ground state iPS cells from human and rat somatic cells.5