VX-702, CAS [[745833-23-2]]

Produktübersicht

• Artikelname: VX-702, CAS [[745833-23-2]]
• Artikelnummer: FBM-10-2181
• Hersteller Artikelnummer: 10-2181
• Alternativnummer: FBM-10-2181-10MG, FBM-10-2181-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 6-[(Aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide

Produktbeschreibung

p38alpha MAP kinase inhibitor

Produkteigenschaften

• Molekulargewicht: 404.32
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [745833-23-2]
• Formel: C19H12F4N4O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: A potent and selective inhibitor of p38 MAP kinases, p38 MAPK and p38 (KD = 3.7 and 17 nM respectively).1 Inhibits IL-6, IL-1 and TNF production in LPS-primed blood.1 Inhibits p38 in platelets stimulated by thrombin, collagen or thromboxane agonist U-46619 at 1 M.2 Provides only modest clinical efficacy in rheumatoid arthritis.3,4 Delays platelet lesions and leads to better maintenance of stored platelets.5