Vandetanib, CAS [[443913-73-3]]

Produktübersicht

• Artikelname: Vandetanib, CAS [[443913-73-3]]
• Artikelnummer: FBM-10-2185
• Hersteller Artikelnummer: 10-2185
• Alternativnummer: FBM-10-2185-10MG, FBM-10-2185-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-yl)methoxy]quinazoline. Alternate Names: ZD6474

Produktbeschreibung

VEGFRK inhibitor

Produkteigenschaften

• Molekulargewicht: 475.35
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: White or off-white solid
• CAS Nummer: [443913-73-3]
• Formel: C22H24BrFN4O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: A potent and selective inhibitor of VEGFR2, (KDR IC50 = 40 nM). Also inhibits fms-like tyrosine kinase 4 (VEGFR3, IC50 = 110 nM) and epidermal growth factor receptor (EGFR/HER1, IC50 = 500 nM) but shows selectivity against a panel of other tyrosine and serine-threonine kinases. Inhibits colony formation in seven cancer cell lines2. Displays anti-angiogenesis activity3.