Vandetanib, CAS [[443913-73-3]]

Product Overview

• Article Name: Vandetanib, CAS [[443913-73-3]]
• Biozol Catalog Number: FBM-10-2185
• Supplier Catalog Number: 10-2185
• Alternative Catalog Number: FBM-10-2185-10MG, FBM-10-2185-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-yl)methoxy]quinazoline. Alternate Names: ZD6474

Product Description

VEGFRK inhibitor

Product Properties

• Molecular Weight: 475.35
• Purity: 98% by TLC, NMR (Conforms)
• Form: White or off-white solid
• CAS Number: [443913-73-3]
• Formula: C22H24BrFN4O2

Application Notes

• Application Notes: A potent and selective inhibitor of VEGFR2, (KDR IC50 = 40 nM). Also inhibits fms-like tyrosine kinase 4 (VEGFR3, IC50 = 110 nM) and epidermal growth factor receptor (EGFR/HER1, IC50 = 500 nM) but shows selectivity against a panel of other tyrosine and serine-threonine kinases. Inhibits colony formation in seven cancer cell lines2. Displays anti-angiogenesis activity3.