Celastrol, CAS [[34157-83-0]]

Produktübersicht

• Artikelname: Celastrol, CAS [[34157-83-0]]
• Artikelnummer: FBM-10-2187
• Hersteller Artikelnummer: 10-2187
• Alternativnummer: FBM-10-2187-5MG, FBM-10-2187-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (9ß,13alpha,14ß,20alpha)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid

Produktbeschreibung

Proteasome inhibitor

Produkteigenschaften

• Molekulargewicht: 450.62
• Reinheit: 98% by TLC, NMR conforms
• Formulierung: Red Solid
• CAS Nummer: [34157-83-0]
• Formel: C29H38O4

Anwendungsbeschreibung

• Anwendungsbeschreibung: Displays potent antioxidant and anti-inflammatory activity. Inhibits NFkappaB (IC50=270 nM). It induces heat shock response and cytoprotection in various cells. Inhibits 20S proteasome chymotrypsin activity (IC50=2.5 µM). Induces autophagy by targeting AR/miR-101 in prostate cancer cells.4 Induces UPR-dependent cell death in cancer cells.5 Cell permeable.