Celastrol, CAS [[34157-83-0]]

Product Overview

• Article Name: Celastrol, CAS [[34157-83-0]]
• Biozol Catalog Number: FBM-10-2187
• Supplier Catalog Number: 10-2187
• Alternative Catalog Number: FBM-10-2187-5MG, FBM-10-2187-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (9ß,13alpha,14ß,20alpha)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid

Product Description

Proteasome inhibitor

Product Properties

• Molecular Weight: 450.62
• Purity: 98% by TLC, NMR conforms
• Form: Red Solid
• CAS Number: [34157-83-0]
• Formula: C29H38O4

Application Notes

• Application Notes: Displays potent antioxidant and anti-inflammatory activity. Inhibits NFkappaB (IC50=270 nM). It induces heat shock response and cytoprotection in various cells. Inhibits 20S proteasome chymotrypsin activity (IC50=2.5 µM). Induces autophagy by targeting AR/miR-101 in prostate cancer cells.4 Induces UPR-dependent cell death in cancer cells.5 Cell permeable.