Cisplatin, CAS [[15663-27-1]]

Produktübersicht

• Artikelname: Cisplatin, CAS [[15663-27-1]]
• Artikelnummer: FBM-10-2204
• Hersteller Artikelnummer: 10-2204
• Alternativnummer: FBM-10-2204-100MG,FBM-10-2204-500MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: Cis-Diaminodichloroplatinum. Alternate Names: CDDP, cis-Diamineplatinum(II) dichloride

Produktbeschreibung

Anticancer agent

Produkteigenschaften

• Molekulargewicht: 300.05
• Reinheit: 98% by HPLC, Elemental Analysis (Conforms)
• Formulierung: Yellow solid
• CAS Nummer: [15663-27-1]
• Formel: Cl2H4N2Pt

Anwendungsbeschreibung

• Anwendungsbeschreibung: Induces intra- and interstrand DNA adducts which poison topoisomerase I.1 Synergizes with topoisomerase I inhibitors such as topotecan.1 Induces apoptosis by sequential activation of caspase-8, -3 and -6 in osteosarcoma cells.2 Inhibits expression of X-linked inhibitor of apoptosis protein (XIAP) in human LNCaP cells.3 Numerous mechanisms inhibit propagation of cisplatin-induced DNA damage to signal apoptosis resulting in resistance.4 Clinically useful anticancer agent.

Bilder

10-2204