Tryptanthrin, CAS [[13220-57-0]]

Produktübersicht

• Artikelname: Tryptanthrin, CAS [[13220-57-0]]
• Artikelnummer: FBM-10-2228
• Hersteller Artikelnummer: 10-2228
• Alternativnummer: FBM-10-2228-5MG, FBM-10-2228-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: Indolo(2,1-b)quinazoline-6,12-dione. Alternate Names: NSC 349447, Couroupitine A

Produktbeschreibung

Immunomodulator, IDO2 inhibitor

Produkteigenschaften

• Molekulargewicht: 248.24
• Reinheit: 98% by HPLC, NMR (Conforms)
• Formulierung: Yellow solid
• CAS Nummer: [13220-57-0]
• Formel: C15H8N2O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: A indoloquinazoline alkaloid found in various plant species and possessing intriguing pharmacological activities.1 Suppresses activation of BV2 microglia cells following LPS treatment and reduces production of proinflammatory cytokines via Nrf2, HO-1 and NFkappaB signaling.2 Displays antiinflammatory activity targeting IL-17.3 Inhibits indoleamine 2,3-dioxygenase 2 (IDO2) with an IC50 of 5-17 µM.4 Induces growth inhibition and neuronal differentiation in human neuroblastoma LA-N-1 cells.5