Tryptanthrin, CAS [[13220-57-0]]

Product Overview

• Article Name: Tryptanthrin, CAS [[13220-57-0]]
• Biozol Catalog Number: FBM-10-2228
• Supplier Catalog Number: 10-2228
• Alternative Catalog Number: FBM-10-2228-5MG, FBM-10-2228-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: Indolo(2,1-b)quinazoline-6,12-dione. Alternate Names: NSC 349447, Couroupitine A

Product Description

Immunomodulator, IDO2 inhibitor

Product Properties

• Molecular Weight: 248.24
• Purity: 98% by HPLC, NMR (Conforms)
• Form: Yellow solid
• CAS Number: [13220-57-0]
• Formula: C15H8N2O2

Application Notes

• Application Notes: A indoloquinazoline alkaloid found in various plant species and possessing intriguing pharmacological activities.1 Suppresses activation of BV2 microglia cells following LPS treatment and reduces production of proinflammatory cytokines via Nrf2, HO-1 and NFkappaB signaling.2 Displays antiinflammatory activity targeting IL-17.3 Inhibits indoleamine 2,3-dioxygenase 2 (IDO2) with an IC50 of 5-17 µM.4 Induces growth inhibition and neuronal differentiation in human neuroblastoma LA-N-1 cells.5