Rotenone, CAS [[83-79-4]]

Produktübersicht

• Artikelname: Rotenone, CAS [[83-79-4]]
• Artikelnummer: FBM-10-2277
• Hersteller Artikelnummer: 10-2277
• Alternativnummer: FBM-10-2277-50MG, FBM-10-2277-1G
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one. Alternate Names: Nicouline, NSC-26285

Produktbeschreibung

Mitochondrial Complex I Inhibitor

Produkteigenschaften

• Molekulargewicht: 394.42
• Reinheit: >98% by HPLC, NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [83-79-4]
• Formel: C23H22O6

Anwendungsbeschreibung

• Anwendungsbeschreibung: Rotenone (83-79-4), the most common member of the rotenoid natural product family, inhibits complex I of the mitochondrial electron transport chain (IC50 = 1.7 - 2.2 µM).1 Also inhibits NADH oxidation by cardiac sarcoplasmic reticulum (IC50 = 3.4 nM).2 May be used to induce Parkinsonism in animal models.3,4 Inhibits autophagy by blocking lysosomal degradation of autophagic vacuoles.5