Rotenone, CAS [[83-79-4]]

Product Overview

• Article Name: Rotenone, CAS [[83-79-4]]
• Biozol Catalog Number: FBM-10-2277
• Supplier Catalog Number: 10-2277
• Alternative Catalog Number: FBM-10-2277-50MG, FBM-10-2277-1G
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one. Alternate Names: Nicouline, NSC-26285

Product Description

Mitochondrial Complex I Inhibitor

Product Properties

• Molecular Weight: 394.42
• Purity: >98% by HPLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [83-79-4]
• Formula: C23H22O6

Application Notes

• Application Notes: Rotenone (83-79-4), the most common member of the rotenoid natural product family, inhibits complex I of the mitochondrial electron transport chain (IC50 = 1.7 - 2.2 µM).1 Also inhibits NADH oxidation by cardiac sarcoplasmic reticulum (IC50 = 3.4 nM).2 May be used to induce Parkinsonism in animal models.3,4 Inhibits autophagy by blocking lysosomal degradation of autophagic vacuoles.5