98% by TLC [5% methanol in methylene chloride + 0.5% HOAc, Rf = 0.21]
Formulierung:
Yellow solid
CAS Nummer:
[518-17-2]
Formel:
C19H17N3O
Anwendungsbeschreibung:
Evodiamine is a quinolone alkaloid isolated from Evodia rutaecarpa.1 Evodia Rutaecarpa is a very popular herb used in traditional chinese medicine to treat a variety of ailments. It has been shown to elicit a variety of biological effects including induction of apoptosis, inhibiting cancer cell proliferation, promoting cell cycle arrest in G2/M, inhibiting invasion and metastasis of cancer cells, inhibiting angiogenesis, induction of oxidative stress and subsequent apoptosis and inhibition of NF-kappaB.2 It also functions as an agonist of TRPV1 (EC50 = 1.03 µM)3 and acts as an anti-inflammatory agent4.
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