Evodiamine, CAS [[518-17-2]]

Product Overview

• Article Name: Evodiamine, CAS [[518-17-2]]
• Biozol Catalog Number: FBM-10-2336
• Supplier Catalog Number: 10-2336
• Alternative Catalog Number: FBM-10-2336-50MG,FBM-10-2336-250MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

TRPV1 agonist, antiinflamatory, antiangiogenic

Product Properties

• Molecular Weight: 303.36
• Purity: 98% by TLC [5% methanol in methylene chloride + 0.5% HOAc, Rf = 0.21]
• Form: Yellow solid
• CAS Number: [518-17-2]
• Formula: C19H17N3O

Application Notes

• Application Notes: Evodiamine is a quinolone alkaloid isolated from Evodia rutaecarpa.1 Evodia Rutaecarpa is a very popular herb used in traditional chinese medicine to treat a variety of ailments. It has been shown to elicit a variety of biological effects including induction of apoptosis, inhibiting cancer cell proliferation, promoting cell cycle arrest in G2/M, inhibiting invasion and metastasis of cancer cells, inhibiting angiogenesis, induction of oxidative stress and subsequent apoptosis and inhibition of NF-kappaB.2 It also functions as an agonist of TRPV1 (EC50 = 1.03 µM)3 and acts as an anti-inflammatory agent4.