Topotecan HCl, CAS [[119413-54-6]]

Produktübersicht

• Artikelname: Topotecan HCl, CAS [[119413-54-6]]
• Artikelnummer: FBM-10-2479
• Hersteller Artikelnummer: 10-2479
• Alternativnummer: FBM-10-2479-10MG, FBM-10-2479-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 10-[(Dimethylamino)methyl]-4S-ethyl-4,9-dihydroxy-1H-pyrano[3,4:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride. Alternate Names: NSC 609669, SKF-104864A

Produktbeschreibung

DNA topoisomerase I inhibitor

Produkteigenschaften

• Molekulargewicht: 457.91
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: Yellow solid
• CAS Nummer: [119413-54-6]
• Formel: C23H23N3O5 HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: Topotecan HCl is a water-soluble and orally active analog of camptothecin, a DNA topoisomerase I inhibitor.1 Inhibits topoisomerase I in human MCF-7 breast and DU-145 prostate cancer cells, IC50s = 13 and 2 nM respectively.2 Downregulates B-Myb and MycN expression in neuroblastoma cells.3 A clinically useful anticancer agent.