Chemical Name: Natural product isolated from Phoma sp
MEK inhibitor
Molekulargewicht:
378.37
Reinheit:
98% by HPLC NMR (Conforms)
Formulierung:
White solid
CAS Nummer:
[76958-67-3]
Formel:
C19H22O8
Anwendungsbeschreibung:
Potent and selective inhibitor of MEK1-3. Acts via covalent binding to Cys residue2. In cells, hypothemycin inhibits the MEK-ERK axis with sufficient selectivity to normalize transformed phenotypes3. Inhibits TNFalpha production in LPS-stimulated macrophages4.
10-2483
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