Hypothemycin, CAS [[76958-67-3]]

Product Overview

• Article Name: Hypothemycin, CAS [[76958-67-3]]
• Biozol Catalog Number: FBM-10-2483
• Supplier Catalog Number: 10-2483
• Alternative Catalog Number: FBM-10-2483-200UG, FBM-10-2483-1MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: Natural product isolated from Phoma sp

Product Description

MEK inhibitor

Product Properties

• Molecular Weight: 378.37
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [76958-67-3]
• Formula: C19H22O8

Application Notes

• Application Notes: Potent and selective inhibitor of MEK1-3. Acts via covalent binding to Cys residue2. In cells, hypothemycin inhibits the MEK-ERK axis with sufficient selectivity to normalize transformed phenotypes3. Inhibits TNFalpha production in LPS-stimulated macrophages4.