Stattic, CAS [[19983-44-9]]

Produktübersicht

• Artikelname: Stattic, CAS [[19983-44-9]]
• Artikelnummer: FBM-10-2524
• Hersteller Artikelnummer: 10-2524
• Alternativnummer: FBM-10-2524-10MG, FBM-10-2524-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 6-Nitrobenzo[b]thiophene 1,1-dioxide

Produktbeschreibung

STAT3 inhibitor

Produkteigenschaften

• Molekulargewicht: 211.20
• Reinheit: 98% by TLC, NMr (Conforms)
• Formulierung: Light yellow solid
• CAS Nummer: [19983-44-9]
• Formel: C8H5NO4S

Anwendungsbeschreibung

• Anwendungsbeschreibung: STAT3 inhibitor. Inhibits binding of tyrosine-phosphorylated peptides to STAT3 SH2 domain and inhibiting STAT3 activation, dimerization and nuclear translocation1. Displays selectivity over STAT1, STAT5, c-Myc/Max, Jun/Jun and Lck. Induces apoptosis in STAT3-dependent cancer cell lines. Alkyates four cysteine residues on STAT32. Exhibits potent antitumor activity3. Protects against angiotensin II-induced vascular dysfunction and hypertension4. An extremely useful tool to probe involvement of STAT3 in cellular signaling.