AS-605240, CAS [[648450-29-7]]

Produktübersicht

• Artikelname: AS-605240, CAS [[648450-29-7]]
• Artikelnummer: FBM-10-2575
• Hersteller Artikelnummer: 10-2575
• Alternativnummer: FBM-10-2575-5MG, FBM-10-2575-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 5-(6-Quinoxalinylmethylene)-2,4-thiazolidine-2,4-dione

Produktbeschreibung

PI 3-Kinase inhibitor

Produkteigenschaften

• Molekulargewicht: 257.27
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: Red solid
• CAS Nummer: [648450-29-7]
• Formel: C12H7N3O2S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent and selective inhibitor of PI 3-kinase (PI 3-K ), IC50 = 8 nM displaying 30-fold selectivity over PI 3-K and PI 3-K and 7.5-fold selectivity over PI 3-K1. Suppresses joint inflammation in two distinct mouse models1. Ameliorates surgical brain injury2, colitis3, intimal hyperplasia-induced inflammatory processes4 and renal injury/fibrosis5 in rodent models. Orally active.