AS-605240, CAS [[648450-29-7]]

Product Overview

• Article Name: AS-605240, CAS [[648450-29-7]]
• Biozol Catalog Number: FBM-10-2575
• Supplier Catalog Number: 10-2575
• Alternative Catalog Number: FBM-10-2575-5MG, FBM-10-2575-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 5-(6-Quinoxalinylmethylene)-2,4-thiazolidine-2,4-dione

Product Description

PI 3-Kinase inhibitor

Product Properties

• Molecular Weight: 257.27
• Purity: 98% by TLC NMR (Conforms)
• Form: Red solid
• CAS Number: [648450-29-7]
• Formula: C12H7N3O2S

Application Notes

• Application Notes: Potent and selective inhibitor of PI 3-kinase (PI 3-K ), IC50 = 8 nM displaying 30-fold selectivity over PI 3-K and PI 3-K and 7.5-fold selectivity over PI 3-K1. Suppresses joint inflammation in two distinct mouse models1. Ameliorates surgical brain injury2, colitis3, intimal hyperplasia-induced inflammatory processes4 and renal injury/fibrosis5 in rodent models. Orally active.