Lycorine HCl, CAS [[2188-68-3]]

Produktübersicht

• Artikelname: Lycorine HCl, CAS [[2188-68-3]]
• Artikelnummer: FBM-10-2608
• Hersteller Artikelnummer: 10-2608
• Alternativnummer: FBM-10-2608-10MG, FBM-10-2608-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: An alkaloid from Amaryllidaceae. Alternate Names: Galanthidine, Amarylline, Narcissine

Produktbeschreibung

Protein synthesis inhibitor/SCAP degrader

Produkteigenschaften

• Molekulargewicht: 323.77
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: White or off-white solid
• CAS Nummer: [2188-68-3]
• Formel: C16H17NO4 HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: Arrests cell cycle at G2/M phase and induces apoptosis in tumor cells.1 Inhibits human enterovirus 71 replication by blocking elongation of the viral polyprotein during translation and reduces viral cytopathic effects in mice.2 Dose-dependently extends the circadian period length in mammalian cells by enhancing Bmal1 transcription.3 Selectively inhibits human ovarian cancer cell proliferation and neovascularization (IC50=1.2 µM4. A potent SREBF chaperone (SCAP) degrader (Kd=15.24 nM) which acts via an autophagy-independent lysosomal pathway.5