Chemical Name: 7a,20-Epoxy-1a,6b,7,14-tetrahydroxykaur-16-en-15-one. Alternate Names: Isodonol
HSP70 inhibitor
Molekulargewicht:
364.43
Reinheit:
98% by TLC NMR (conforms)
Formulierung:
White of off-white solid
CAS Nummer:
[28957-04-2]
Formel:
C20H28O6
Anwendungsbeschreibung:
A potent, covalent inhibitor of the NLRP3 inflammasome with anti-inflammatory activity in various mouse models.1 Inhibits vascular inflammation in vivo.2 Inhibits aberrant AKT activation in human breast cancer cells with hyperactivated PI3K/AKT signaling.3 Inhibits migration, invasion and adhesion of melanoma cells.4 Induces apoptosis in osteosarcoma cells by multiple pathways.5
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