Chemical Name: 7a,20-Epoxy-1a,6b,7,14-tetrahydroxykaur-16-en-15-one. Alternate Names: Isodonol
HSP70 inhibitor
Molecular Weight:
364.43
Purity:
98% by TLC NMR (conforms)
Form:
White of off-white solid
CAS Number:
[28957-04-2]
Formula:
C20H28O6
Application Notes:
A potent, covalent inhibitor of the NLRP3 inflammasome with anti-inflammatory activity in various mouse models.1 Inhibits vascular inflammation in vivo.2 Inhibits aberrant AKT activation in human breast cancer cells with hyperactivated PI3K/AKT signaling.3 Inhibits migration, invasion and adhesion of melanoma cells.4 Induces apoptosis in osteosarcoma cells by multiple pathways.5
* VAT and and shipping costs not included. Errors and price changes excepted