Monastrol, CAS [[254753-54-3]]

Produktübersicht

• Artikelname: Monastrol, CAS [[254753-54-3]]
• Artikelnummer: FBM-10-2629
• Hersteller Artikelnummer: 10-2629
• Alternativnummer: FBM-10-2629-5MG,FBM-10-2629-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Kinesin Eg5 and mitosis inhibitor

Produkteigenschaften

• Molekulargewicht: 292.35
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: Beige solid
• CAS Nummer: [254753-54-3]
• Formel: C14H16N2O3S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent, cell-permeable, small molecule inhibitor of mitosis. Monastrol-arrested cells are characterized by monopolar spindles.1 Does not affect other motor proteins or tubulin. Specifically inhibits the mitotic molecular motor kinesin Eg5, a motor protein required for spindle formation (IC50 = 14 µM).2 Mimics the effect of amyloid beta on long term potentiation in a cellular model of learning and memory.3 Enhances regeneration of adult axons.4