Migalastat, CAS [[75172-81-5]]

Produktübersicht

• Artikelname: Migalastat, CAS [[75172-81-5]]
• Artikelnummer: FBM-10-2632
• Hersteller Artikelnummer: 10-2632
• Alternativnummer: FBM-10-2632-1MG,FBM-10-2632-5MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: 1-deoxygalactonojirimycin, DDIG, AT1001, DGJ, GR181413

Produktbeschreibung

Galactosidase inhibitor, pharmacological chaperone

Produkteigenschaften

• Molekulargewicht: 199.63
• Reinheit: >98% by TLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [75172-81-5]
• Formel: C6H13NO4 HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: Migalastat is a potent, selective, and orally available inhibitor of alpha-galactosidase A (IC50= 40 nM).1 It binds to mutant misfolded alpha-GalA shifting the folding behavior toward functional active conformation (pharmacological chaperone activity) followed by trafficking to the lysosomes.2 Migalastat is active broadly across species from Drosophila3 to human4. Clinically useful agent for Fabry disease.5