2-Deoxy-5-fluorocytidine, CAS [[10356-76-0]]

Produktübersicht

• Artikelname: 2-Deoxy-5-fluorocytidine, CAS [[10356-76-0]]
• Artikelnummer: FBM-10-2685
• Hersteller Artikelnummer: 10-2685
• Alternativnummer: FBM-10-2685-5MG,FBM-10-2685-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: FCDR, FdCyd, NSC-48006, Ro 5-1090

Produktbeschreibung

Irreversible DNA methyl transferase inhibitor

Produkteigenschaften

• Molekulargewicht: 245.21
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [10356-76-0]
• Formel: C9H12FN3O4

Anwendungsbeschreibung

• Anwendungsbeschreibung: A DNA methyltransferase inhibitor currently in clinical trials for breast cancer and other solid tumors1. Like 5-Azacytidine and decitabine, 2-Deoxy-5-fluorocytidine is a pyrimidine analog that integrates into chromatin to inhibit DNA methylation2. It blocks proliferation in colon cancer-derived HCT116 cells by activating DNA response pathways3. It inhibits various strains of pathogenic avian influenza viruses in vitro and in vivo4.