2-Deoxy-5-fluorocytidine, CAS [[10356-76-0]]

Product Overview

• Article Name: 2-Deoxy-5-fluorocytidine, CAS [[10356-76-0]]
• Biozol Catalog Number: FBM-10-2685
• Supplier Catalog Number: 10-2685
• Alternative Catalog Number: FBM-10-2685-20MG, FBM-10-2685-100MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 5-fluoro-2deoxycytidine. Alternate Names: FCDR, FdCyd, NSC-48006, Ro 5-1090

Product Description

Irreversible DNA methyl transferase inhibitor

Product Properties

• Molecular Weight: 245.21
• Purity: 98% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [10356-76-0]
• Formula: C9H12FN3O4

Application Notes

• Application Notes: A DNA methyltransferase inhibitor currently in clinical trials for breast cancer and other solid tumors1. Like 5-Azacytidine and decitabine, 2-Deoxy-5-fluorocytidine is a pyrimidine analog that integrates into chromatin to inhibit DNA methylation2. It blocks proliferation in colon cancer-derived HCT116 cells by activating DNA response pathways3. It inhibits various strains of pathogenic avian influenza viruses in vitro and in vivo4.