Scriptaid, CAS [[287383-59-9]]

Produktübersicht

• Artikelname: Scriptaid, CAS [[287383-59-9]]
• Artikelnummer: FBM-10-2712
• Hersteller Artikelnummer: 10-2712
• Alternativnummer: FBM-10-2712-5MG,FBM-10-2712-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-N-hydroxyhexanamide. Alternate Names: Scriptide, GCK1026

Produktbeschreibung

HDAC inhibitor

Produkteigenschaften

• Molekulargewicht: 326.35
• Reinheit: 98% by TLC NMR (conforms)
• Formulierung: White solid
• CAS Nummer: [287383-59-9]
• Formel: C18H18N2O4

Anwendungsbeschreibung

• Anwendungsbeschreibung: Inhibits histone deacetylases (HDAC) 1 and 3 (IC50~0.6 M) and HDAC8 (IC50~1 M) and is less toxic compared to trichostatin A.1,2 Induces cell cycle arrest and epigenetic changes in colon cancer cells.3 Together with DRB-inhibition of RNA synthesis, scriptaid enhances gene reprogramming in somatic cell nuclear transfer (SCNT) embryos.4 Increases exercise endurance in mice.5

Bilder

10-2712