Scriptaid, CAS [[287383-59-9]]

Product Overview

• Article Name: Scriptaid, CAS [[287383-59-9]]
• Biozol Catalog Number: FBM-10-2712
• Supplier Catalog Number: 10-2712
• Alternative Catalog Number: FBM-10-2712-5MG, FBM-10-2712-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-N-hydroxyhexanamide. Alternate Names: Scriptide, GCK1026

Product Description

HDAC inhibitor

Product Properties

• Molecular Weight: 326.35
• Purity: 98% by TLC NMR (conforms)
• Form: White solid
• CAS Number: [287383-59-9]
• Formula: C18H18N2O4

Application Notes

• Application Notes: Inhibits histone deacetylases (HDAC) 1 and 3 (IC50~0.6 M) and HDAC8 (IC50~1 M) and is less toxic compared to trichostatin A.1,2 Induces cell cycle arrest and epigenetic changes in colon cancer cells.3 Together with DRB-inhibition of RNA synthesis, scriptaid enhances gene reprogramming in somatic cell nuclear transfer (SCNT) embryos.4 Increases exercise endurance in mice.5