Chemical Name: 2R-(Hydroxymethyl)-3R,4R,5R-piperidinetriol hydrochloride. Alternate Names: 1,5-Dideoxy-1,5-imino-D-mannitol hydrochloride
Mannosidase inhibibitor
Molekulargewicht:
199.63
Reinheit:
98% by TLC, NMR (Conforms)
Formulierung:
White solid
CAS Nummer:
[73465-43-7]
Formel:
C6H13NO4 HCl
Anwendungsbeschreibung:
Potent and selective inhibitor of alpha-mannosidase I.1,2 Inhibits the conversion of high mannose to complex oligosaccharides.3 Attenuates tunicamycin-, thapsigargin- and Abeta1-42-induced ER stress dependent neuronal cell death and protects primary cultured mouse cortical neurons from Abeta1-42 toxicity.4 Increases titers (4 fold) in the production of lentivirus vectors with enhanced efficiency in targeting dendritic cells.5,6
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten