Z-DEVD-FMK, CAS [[210344-95-9]]

Produktübersicht

• Artikelname: Z-DEVD-FMK, CAS [[210344-95-9]]
• Artikelnummer: FBM-10-2904
• Hersteller Artikelnummer: 10-2904
• Alternativnummer: FBM-10-2904-1MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: Benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone

Produktbeschreibung

Caspase3 inhibitor (cell permeable)

Produkteigenschaften

• Molekulargewicht: 668.67
• Reinheit: >98% by TLC, NMR (Conforms)
• Formulierung: Lyophilized solid
• CAS Nummer: [210344-95-9]
• Formel: C30H41FN4O12

Anwendungsbeschreibung

• Anwendungsbeschreibung: Z-DEVD-FMK (210344-95-9) is a cell-permeable trimethyl ester form of the irreversible caspase-3 inhibitor DEVD-FMK (fluoromethylketone) with IC50 = 130 nM.1,2 Methyl esters confer cell permeability and are hydrolyzed to the active COOH form via intracellular esterases. Inhibits caspase-3-dependent apoptosis and pyroptosis in a variety of cell lines.3,4 Active in vivo.5