Z-DEVD-FMK, CAS [[210344-95-9]]

Product Overview

• Article Name: Z-DEVD-FMK, CAS [[210344-95-9]]
• Biozol Catalog Number: FBM-10-2904
• Supplier Catalog Number: 10-2904
• Alternative Catalog Number: FBM-10-2904-1MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Caspase3 inhibitor (cell permeable)

Product Properties

• Molecular Weight: 668.67
• Purity: >98% by TLC, NMR (Conforms)
• Form: Lyophilized solid
• CAS Number: [210344-95-9]
• Formula: C30H41FN4O12

Application Notes

• Application Notes: Z-DEVD-FMK (210344-95-9) is a cell-permeable trimethyl ester form of the irreversible caspase-3 inhibitor DEVD-FMK (fluoromethylketone) with IC50 = 130 nM.1,2 Methyl esters confer cell permeability and are hydrolyzed to the active COOH form via intracellular esterases. Inhibits caspase-3-dependent apoptosis and pyroptosis in a variety of cell lines.3,4 Active in vivo.5