Chemical Name: Benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone
Caspase3 inhibitor (cell permeable)
Molecular Weight:
668.67
Purity:
>98% by TLC, NMR (Conforms)
Form:
Lyophilized solid
CAS Number:
[210344-95-9]
Formula:
C30H41FN4O12
Application Notes:
Z-DEVD-FMK (210344-95-9) is a cell-permeable trimethyl ester form of the irreversible caspase-3 inhibitor DEVD-FMK (fluoromethylketone) with IC50 = 130 nM.1,2 Methyl esters confer cell permeability and are hydrolyzed to the active COOH form via intracellular esterases. Inhibits caspase-3-dependent apoptosis and pyroptosis in a variety of cell lines.3,4 Active in vivo.5
* VAT and and shipping costs not included. Errors and price changes excepted
